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“In particular, the findings show that whole-body energy metabolism, which is known to be impaired in overt hypothyroidism, measured using indirect calorimetry, was not fully normalized in women with obesity and long-lasting hypothyroidism taking the right dose of levothyroxine in comparison with women who are obese without hypothyroidism.” In an observational, retrospective study, Perseghin and colleagues analyzed data from a cohort of women with obesity but without diabetes and normal thyroid-stimulating hormone levels (range, 0.4-4 mUI/L) who attended a standard protocol for bariatric surgery between January 2013 and July 2019